DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan dbco-lys-m-PEG4 Product Name Thalidomide-O-acetamido-PEG1-C2-acid Synonyms Thalidomide-4'-O-acetamido-PEG1-C2-acid

Product Name Thalidomide-O-acetamido-PEG1-C2-acid Synonyms Thalidomide-4'-O-acetamido-PEG1-C2-acid CAS Number 2204225-99-8 Related CAS Molecular Formula C20H21N3O9 Molecular Weight 447

ZXH-1-161 is a potent cereblon (CRBN) modulator with an IC50 value of 39 nM in MM1

NCCCCCCC(=O)NC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

TMR C2 maleimides have higher labeling efficiency

DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan dbco-lys-m-PEG4 Product Name Thalidomide-O-acetamido-PEG1-C2-acid Synonyms Thalidomide-4'-O-acetamido-PEG1-C2-acidSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further