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28 When cellular iron is sufficient, transferrin-bound iron is reduced to limit excess iron accumulation

Therefore, all procedures performed involving human tissue donors were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards

Oxidative stress-related issues: Individuals may be more susceptible to oxidative stress, leading to various health problems related to tissue damage and inflammation

Circadian rhythms are endogenous, approximately 24-h oscillations that govern key physiological and metabolic processes in synchrony with environmental cues